Gout is a form of inflammatory arthritis caused by the deposition of uric-acid crystals in the joints. It typically begins with sudden, excruciating pain in the big toe but can affect any joint. With correct long-term uric-acid control, gout is one of the few forms of arthritis that can be fully prevented from recurring.
Symptoms
Sudden, intense joint pain — often starting at night
Swelling, redness and warmth of the affected joint
Limited range of motion during and after an attack
Recurrent flares if uric acid is not controlled
Tophi (uric-acid nodules) in longstanding disease
Causes
Elevated blood uric-acid levels (hyperuricaemia)
Genetic predisposition
Diet rich in red meat, organ meats, seafood and sugary drinks
Alcohol — particularly beer
Certain medications and kidney disease
Diagnosis
Serum uric-acid measurement
Joint fluid analysis to identify uric-acid crystals
Ultrasound to visualise crystal deposits
Assessment of kidney function and cardiovascular risk
Treatment Options
NSAIDs, colchicine or short-course steroids for acute flares